Projects & Grants

Prevalence of Helicobacter pylori infection in patients with a high degree of obesity
Project IdSGS20/LF/2023
Main solverMgr. Adéla Novotná
Period1/2023 - 12/2023
ProviderSpecifický VŠ výzkum
AnotationThe possibilities of influencing obesity and associated comorbidities with metabolic surgery methods have been known for a long time. The success of this obesity treatment depends to a large extent on cooperation, psychological support, dispensary of the patient and adherence to the correct dietary regimen and recommended regimen measures. A very effective way of treating obesity is bariatric surgery, which reduces the incidence of obesity-related comorbidities and also leads to significant and permanent weight loss, which is associated with an improvement in quality of life and a longer lifespan. Before a bariatric procedure, a patient should undergo a comprehensive, comprehensive assessment by a multidisciplinary team, including endocrinologists, dieticians, psychologists, anesthesiologists, nurses, cardiologists and a surgeon. As part of the examination algorithm, clinically significant gastrointestinal symptoms should be evaluated using imaging methods or endoscopy before the procedure. During diagnostic gastroscopy, it is important to determine the presence of Helicobacter pylori, especially in the light of recent studies demonstrating the connection between the presence of H. pylori and the occurrence of marginal ulcers after surgery, especially after RYGB. H. pylori is an important human pathogen representing one of the most common bacteria infecting approximately half of the world's population and causing atrophic gastritis, gastroduodenal ulcer, gastric cancer, idiopathic thrombocytopenic purpura, iron deficiency anemia and vitamin B12 deficiency. H. Pylori infection is the most common chronic infection in humans. Known risk factors include poor socioeconomic status and living conditions, especially at a young age. In the Czech Republic, the prevalence is estimated at 22 to 25%. The relationship between BMI and HP infection is controversial. Some data suggest that HP infection occurs less frequently in overweight individuals.