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UO > About > Organizational Structure > Faculties & Institutes > Faculty of Medicine > Departments & Centres > Centre for Health Research

Dhwani Radhakrishnan


Academic degree, name, surname:
Dhwani Radhakrishnan, Ph.D.
Room, floor, building:
Position:
Research interests and teaching:
Department (Faculty):
Head and Neck Cancer Research Group (Faculty of Medicine)
Phone number, mobile:
E-mail:



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Deubiquitinase BAP1 is crucial for surface expression of T cell receptor (TCR) complex, T cell-B cell conjugate formation, and T cell activation
Dhwani Radhakrishnan, Jana Kotulová, Lucie Hofmanová, Anjana Anilkumar Sithara, Marcello Turi, David ŽIHALA, Michal Ďurech, Jan VRÁNA, Valeria Uleri, Veronika Niederlova, Stepanek Ondrej, Zuzana Chyra, Tomáš Jelínek, Roman Hájek, Matouš Hrdinka ... other authors
Year: 2025, Journal of Leukocyte Biology
journal article
 
Transcriptome Analysis of Diffuse Large B-Cell Lymphoma Cells Inducibly Expressing MyD88 L265P Mutation Identifies Upregulated CD44, LGALS3, NFKBIZ, and BATF as Downstream Targets of Oncogenic NF-κB Signaling
Marcello Turi, Anjana Anilkumar Sithara, Lucie Hofmanová, David ŽIHALA, Dhwani Radhakrishnan, Alexander Vdovin, Sofija Knápková, Tereza Ševčíková, Zuzana Chyra, Tomáš Jelínek, Michal Šimíček, Annamaria Gulla, Kenneth Carl Anderson, Roman Hájek, Matouš Hrdinka ... other authors
Year: 2023, International Journal of Molecular Sciences
journal article
 
Tuning CARs: recent advances in modulating chimeric antigen receptor (CAR) T cell activity for improved safety, efficacy, and flexibility
Piotr Celichowski, Marcello Turi, Sandra Charvátová, Dhwani Radhakrishnan, Neda Feizi, Zuzana Chyra, Michal Šimíček, Tomáš Jelínek, Julio Rodriguez Bago, Roman Hájek, Matouš Hrdinka ... other authors
Year: 2023, Journal of Translational Medicine
journal article
 
The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma
Alexander Vdovin, Tomáš Jelínek, David ŽIHALA, Tereza Ševčíková, Michal Ďurech, Hana Šahinbegović, Renáta Šnaurová, Dhwani Radhakrishnan, Marcello Turi, Zuzana Chyra, Tereza Popková, Ondřej Venglář, Matouš Hrdinka, Roman Hájek, Michal Šimíček ... other authors
Year: 2022, Nature Communications
journal article
 

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Research of molecular basis of hematological malignancies and novel biomarkers for targeted cell therapy
Period
1/2023 – 12/2023
Provider
Specifický VŠ výzkum
State
finished
Role in the project
Co-Investigator
Total costs
931 322 CZK
 
The composition of NOD1/2-RIPK2 receptor complexes and their pro-survival signaling functions in the pathology of Multiple Myeloma
Period
9/2021 – 2/2023
Provider
Katedra biologie a ekologie, DGC
State
finished
Role in the project
Co-Investigator
Total costs
1 293 732 CZK
 
Analysis of selected cellular signaling pathways responsible for pathogenesis and drug resistance in hematological malignancies
Period
1/2022 – 12/2022
Provider
Specifický VŠ výzkum
State
finished
Role in the project
Co-Investigator
Total costs
630 000 CZK
 
Immunophenotypic characterisation of NK cells in patients with multiple myeloma and immune-monitoring of NK cells during standard anti-myeloma treatment
Period
1/2021 – 12/2021
Provider
Specifický VŠ výzkum
State
finished
Role in the project
Co-Investigator
Total costs
610 000 CZK
 

Centre for Health Research

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