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UO > About > Organizational Structure > Faculties & Institutes > Faculty of Medicine > Departments & Centres > Centre for Health Research > Vivarium

Michal Šimíček


Academic degree, name, surname:
doc. RNDr. Michal Šimíček, PhD.
Room, floor, building:
Position:
Head of Department
Research interests and teaching:
Department (Faculty):
Department of Haematooncology (Faculty of Medicine)
Medical Research Center (Faculty of Medicine)
Phone number, mobile:
E-mail:



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Author
Title
Type of thesis
Year
Šahinbegović Hana
Homeostasis and Malignancy: Insights into Cellular Mechanisms
Doctoral thesis
2023
Šnaurová Renáta
The Deubiquitinase OTUD1 Affects the Processivity of Translation
Doctoral thesis
2023
Vdovin Alexander
Molecular mechanism of immunoglobulin production involved in resistance to  proteasome inhibitors
Doctoral thesis
2023
Heczková Markéta
Analysis of CD3e lateral interaction partners using proximity tagging method
Master's thesis
2024
Garbová Nikola
Identification of lateral interactions of CD19 partners using the PUP-IT method
Master's thesis
2022
Chrástecká Leona
The role of deregulated signaling pathways in the pathogenesis and therapeutic targeting of multiple myeloma
Bachelor's thesis
2025



Extramedullary multiple myeloma: molecular pathogenesis and novel therapeutical targets
Main solver
doc. RNDr. Michal Šimíček, PhD.
Period
5/2023 - 12/2026
Provider
Agentura zdravotnického výzkumu ČR
State
solved
 
Genetically modified donor T cells as a universal cell source for the immunotherapy of tumors using T lymphocytes equipped with a chimeric antigen receptor (CAR).
Main solver
doc. RNDr. Michal Šimíček, PhD.
Period
8/2019 - 12/2022
Provider
Program TRIO
State
finished
 
Identification and functional validation of mutations in multiple myeloma patients resistant to therapy with proteasomal inhibitors
Main solver
doc. RNDr. Michal Šimíček, PhD.
Period
1/2018 - 12/2020
Provider
Katedra interních oborů, MŠMT
State
finished
 
Molecular characterization of newly identified protein markers in residual multiple myeloma resistant to antitumor therapy
Main solver
doc. RNDr. Michal Šimíček, PhD.
Period
1/2019 - 12/2020
Provider
Specifický VŠ výzkum
State
finished
 
Organoid systems for modeling of bone marrow environment in the development of multiple myeloma
Main solver
doc. RNDr. Michal Šimíček, PhD.
Period
1/2019 - 12/2020
Provider
Specifický VŠ výzkum
State
finished
 
Detection of new biomarkers in resistance to Venetoclax
Main solver
doc. RNDr. Michal Šimíček, PhD.
Period
1/2018 - 12/2019
Provider
Specifický VŠ výzkum
State
finished
 

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